Patrick Dempsey Says “Grey's Anatomy” Fame Made Him 'Much More of a Homebody'

Patrick Dempsey Says

Patrick Dempsey says the success of Grey's Anatomy led him to become more of a "homebody"

People Patrick Dempsey on 'Grey's Anatomy' (left); Patrick Dempsey on Jan. 28, 2026 in New York CityCredit: Frank Ockenfels/Disney General Entertainment Content via Getty; Jason Mendez/Getty

NEED TO KNOW

  • In a new interview, the actor said the show's popularity initially "really infringed upon our ability to go out to be social"

  • Dempsey joined Grey's in the first season, which aired in 2005, and left in a shocking twist in season 11

Patrick Dempseyis sharing how his popularity onGrey's Anatomycaused him to become more introverted.

In an interview published on Monday, March 16, the 60-year-old actor spoke toThe Hollywood Reportermore than a decade after he leftGrey's Anatomyas Dr. Derek Shepherd (aka McDreamy), a love interest to series protagonist Meredith Grey, played byEllen Pompeo.

"I think in the heat of the success of [Grey's], it really infringed upon our ability to go out to be social and to be private, and that's kept us at home a lot more," Dempsey said of himself and his family. "I'm much more of a homebody. I'm aware of my responsibility when I go out. I want to be present, and if people come up to me, I want to make sure I engage and talk to them and greet them or take a picture."

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Ellen Pompeo (left) and Patrick Dempsey on 'Grey's Anatomy'Credit: Michael Ansell/Disney General Entertainment Content via Getty

He continued: "It's sometimes very difficult with the family, because we could be having this intimate moment and sometimes people cross the line. And they don't mean to be rude, but it's very hard. That's part of the position you're in [as a public figure], and you have to accept that — and they have over time."

His kids, he added, now "understand the role, and when they come out with me now, they have much greater appreciation of, like, 'Oh, what is important when you go out?' They're learning at this age. It's better than when they were younger."

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Dempsey, who is currently starring on Fox'sMemory of a Killer, joinedGrey'sin the first season, which aired in 2005. In a shocking twist, his character Derekgot killed offin season 11, when he was struck by a truck just after saving strangers from an earlier car wreck.

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He made a reappearance on the show in 2020, during a dream sequence inthe season 17 premiere.

Speaking toTHR, Dempsey said Derek "will always be a part of my life."

"I accepted that a long time ago. It's nice to be able to go and do something else — and to be allowed to do something else — and hopefully the audience will accept me and come along on these new journeys as an actor to explore different types of characters," he added.

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